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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
13.64
Human Site:
S745
Identified Species:
27.27
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
S745
Q
A
T
N
A
K
D
S
G
C
S
S
P
G
A
Chimpanzee
Pan troglodytes
XP_526584
753
86517
S745
Q
A
T
N
A
K
D
S
G
C
S
S
P
G
A
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
S745
Q
A
T
N
A
K
D
S
G
C
N
S
P
G
A
Dog
Lupus familis
XP_544934
970
109306
Q951
Q
A
T
N
T
D
N
Q
A
A
N
Q
A
N
T
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
S749
Q
S
T
D
T
A
E
S
G
H
S
S
P
G
P
Rat
Rattus norvegicus
Q3SWT6
640
73948
T633
Y
V
V
H
K
Y
E
T
P
E
S
P
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
D857
L
L
N
G
A
P
A
D
G
P
V
P
L
A
G
Chicken
Gallus gallus
XP_420595
713
82896
F706
F
N
E
F
L
E
A
F
R
L
V
K
Q
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
D711
F
R
V
V
H
K
L
D
V
K
E
Q
Q
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
K654
D
P
T
D
C
E
S
K
V
I
D
P
K
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
A687
Q
N
S
P
A
H
V
A
N
G
E
N
N
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
K301
Q
I
L
K
P
A
E
K
K
Q
K
F
G
R
R
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
100
93.3
26.6
N.A.
53.3
6.6
N.A.
13.3
0
N.A.
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
40
N.A.
73.3
26.6
N.A.
13.3
6.6
N.A.
6.6
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
42
17
17
9
9
9
0
0
9
9
25
% A
% Cys:
0
0
0
0
9
0
0
0
0
25
0
0
0
0
0
% C
% Asp:
9
0
0
17
0
9
25
17
0
0
9
0
0
0
0
% D
% Glu:
0
0
9
0
0
17
25
0
0
9
17
0
0
0
0
% E
% Phe:
17
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
42
9
0
0
9
34
17
% G
% His:
0
0
0
9
9
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
9
9
34
0
17
9
9
9
9
9
17
9
% K
% Leu:
9
9
9
0
9
0
9
0
0
9
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
9
34
0
0
9
0
9
0
17
9
9
17
0
% N
% Pro:
0
9
0
9
9
9
0
0
9
9
0
25
34
0
9
% P
% Gln:
59
0
0
0
0
0
0
9
0
9
0
17
17
9
9
% Q
% Arg:
0
9
0
0
0
0
0
0
9
0
0
0
0
9
9
% R
% Ser:
0
9
9
0
0
0
9
34
0
0
34
34
0
9
9
% S
% Thr:
0
0
50
0
17
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
9
17
9
0
0
9
0
17
0
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _